Can increased uric acid cause itching
Those already present will start dissolving. While the skin rash sometimes can be serious, other side effects usually are not serious and may go away as your body gets used to the medicine. If any side effects continue to bother you, contact your doctor.
Take these medications with plenty of liquids. Do not take aspirin with these drugs because it blocks their effects on the kidneys. Read the labels of any prescription or over-the-counter medicines you take to be sure they don't contain aspirin. At first, probenecid or sulfinpyrazone may increase your risk for kidney stones by increasing the uric acid content of the urine.
To prevent this problem, keep your urine diluted by drinking eight ounce glasses of fluid every day. Probenecid, sulfinpyrazone and allopurinol also may cause you to have more frequent gout episodes at first.
During this time, you may have to take colchicine or an NSAID for the first three to six months to prevent an episode. Take your medicine exactly as your doctor instructs. In order to be effective, these medicines must be taken continuously. This will help your body get rid of excess uric acid and will keep the uric acid level from rising again. Do not take double doses of your medicine.
If you forget to take a dose, take it as soon as possible. However, if it is almost time for your next dose, skip the dose you missed. Talk with your doctor about all the drugs you're taking. This includes over-the-counter drugs such as aspirin or diuretics. Some of the gout medications will not work properly if you are taking other drugs at the same time. Don't start any new drugs without being sure they will work properly with the ones you're already taking.
The amount of medications you take will depend upon your symptoms and laboratory test results. You may only need to take one drug. On the other hand, it may be necessary to take a combination of the drugs listed here.
Not all people with gout require these drugs. Whether you take these drugs depends on your doctor's judgment and your willingness to make a lifelong commitment to taking daily medications. Surgery is rarely used to treat gout. If you have large tophi that are draining, infected or are interfering with the movement of your joints, you and your doctor may decide to have them surgically removed. There are several kinds of operations that can be done to relieve pain and improve the function of the affected joints.
Some of this material may also be available in an Arthritis Foundation brochure. Adapted from the pamphlet originally prepared for the Arthritis Foundation by Louis A. Healey, Jr. Diamond, M. This material is protected by copyright. You are here Home Gout. Facts and myths Gout once was mistakenly thought to be a disease of the wealthy because it seemed to be caused by eating rich foods and by drinking too much alcohol. Prognosis Gout affects everyone differently.
Incidence Gout affects more than one million Americans from all walks of life. Symptoms Attacks of gout usually develop very quickly. Gout usually affects only one or two joints at a time - most often the feet and ankles. The ball of the big toe is the commonest site. Without treatment the attack subsides in a week or so and when patients first develop gout there may be intervals of many months or even years between attacks.
As time goes by, these tend to become more frequent and more severe and eventually many joints may be involved, sometimes all at the same time.
Gout thus occurs in individuals who have higher than normal levels of uric acid in blood. This may be due to genetic factors, obesity, high alcohol intake, high intake of food containing purines red meat, fish, and vegetables like cauliflower, spinach, mushrooms, green peas and some drugs used to treat high blood pressure etc. You can get your uric acid level tested and consult a doctor.
What Is Zika Virus? Gout comes from gutta , Latin for drop, a reference to the belief that it was caused by a drop-by-drop accumulation of humors in the joints. But gout is still very much with us, and the number of Americans affected seems to be increasing, at least partly because of the obesity epidemic.
Gout remains a disease that mainly affects middle-aged and older men, although postmenopausal women are vulnerable too, perhaps because they lack the protective effect of estrogen. The diuretics "water pills" that many people take to control high blood pressure are another contributing factor.
Gout can also be a problem for transplant recipients. There are several reasons for this but medications, such as cyclosporine, taken to reduce the chances of organ rejection and reduced kidney function are major contributors. The encouraging news is that almost all gout cases are treatable.
In fact, gout is one of the few treatable and preventable forms of arthritis, an umbrella term for dozens of conditions that cause inflammation in the joints. The challenge is making sure people get the gout care they need and follow through on taking medications. Purines are a group of chemicals present in all body tissues and in many foods. Our bodies are continually processing purines, breaking them down and recycling or removing the byproducts.
Uric acid is one of the byproducts and, normally, any excess leaves in the urine. But in some people, the system for keeping levels in check falls out of kilter. Usually it's because the kidneys aren't keeping up and excreting enough uric acid, but sometimes it's a matter of too much uric acid being produced or it's a combination of both.
Gout occurs when surplus uric acid coalesces into crystals, which causes inflammation in the joints. Pain, swelling and loss of joint motion are typical. Technically, the crystals consist of sodium urate, although for simplicity's sake they're often referred to as uric acid crystals.
The crystals appear most often in the joints, but they may also collect elsewhere, including the outer ear, in the skin near the joints, and the kidney. High concentrations of uric acid levels in the blood — the medical term is hyperuricemia — are necessary for the crystals to form. Yet many people with hyperuricemia never develop gout, and even when they do, they often have had high levels of uric acid in their blood for years without any symptoms.
People with hyperuricemia with no symptoms might be coached to make lifestyle changes — losing weight would often top the list — but hyperuricemia by itself is usually not treated. Hyon K. Choi, now at the Massachusetts General Hospital in Boston, and epidemiologists at Harvard have used data from the Harvard-based, all-male Health Professionals Follow-up Study to make a series of comparisons between the men in this study who developed gout during a year period and the vast majority of those in the study who did not.
The result is an impressive dossier on the risk factors for gout, at least as they pertain to men. Choi's findings on weight weren't surprising and fit the stereotype: gout is, in fact, a heavy man's disease.
Eating lots of meat and seafood and drinking lots of alcohol spells gouty trouble. And the Homer Simpsons of the world are gout candidates: two-or-more-a-day beer drinkers are more than twice as likely to get gout as nonbeer drinkers, which makes sense, because beer contains a lot of purines.
Side effects of these medications can include bleeding, stomach ulcers, and stomach pain. Colchicine Colcrys can reduce gout pain, but side effects may include nausea, diarrhea, and vomiting. Corticosteroids such as prednisone also reduce inflammation and pain. These prescription medications can be taken orally or injected into your joint.
Side effects include mood changes, elevated blood pressure, and water retention. There are medications that block the production of uric acid and others that help your body remove uric acid, such as allopurinol Zyloprim and probenecid, respectively. Take medication as directed. Limiting your intake of alcohol and beverages with high-fructose corn syrup can reduce the likelihood of an attack.
You can also prevent a gout attack by increasing your intake of water and decreasing your intake of meat, poultry, and other high-purine foods. Losing excess pounds also helps maintain a healthy uric acid level. More than 8 million Americans have gout, a condition that causes painful inflammation in the joints. Learn the symptoms, what causes it, and how it's….
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